Corneal crosslinking for keratoconus: stability or improvement

Track:
Cornea
What:
Paper Presentation | Présentation d'article
When:
3:20 PM, Saturday 26 Jun 2021 (5 minutes)

Authors: Maryam Eslami, Sonia Yeung, Farhad Ghaseminejad, Paul J. Dubord, Alfonso Iovieno.

Disclosure Block: M. Eslami: None. S. Yeung: None. F. Ghaseminejad: None. P.J. Dubord: None. A. Iovieno: None.

Abstract Title: Corneal Collagen Crosslinking for Keratoconus: Stability or Improvement?

Abstract Body:

Purpose: to analyze long term outcomes of corneal collagen cross-linking (CXL) for keratoconus.

Study Design: Retrospective observational study.

Methods: Review of patients with keratoconus who underwent CXL with a minimum follow-up of 5 years. Patients’ refractive and topographic data (corrected distance visual acuity (CDVA), sphere, cylinder, average and maximum keratometry, corneal aberrations) were collected pre-CXL and at 3 years, 5 years, 7 years and beyond if available.

Results: 112 patients/150 eyes (mean age: 33.2 ±10.7 years; range: 13-61) were included. Mean follow-up was 5.87±1.35 years (range: 5-10). A progressive improvement in CDVA, spherical and cylindrical refraction, average and steepest keratometry and corneal aberrations was observed at the last follow up visit(p<0.05). While 66% of eyes showed stability of mean-K at the last follow up visit, 28.7% displayed topographic flattening beyond 1D and 13.3% beyond 2D. Moreover, 35.5% and 22.0% of eyes had improvement beyond 1D in their spherical and cylindrical power respectively. There was also a statistically significant reduction of all corneal wavefront aberrations and corneal RMS compared to the preoperative values, with the exception of Trefoil.

Conclusions: When long term outcomes are considered, collagen cross-linking for keratoconus not only halts the progression but can induce an amelioration of topographical indexes and corneal aberrations thereby improving visual acuity and refraction.


Speaker
2022 Planning Committee/Council of Canadian Ophthalmology Residents (Vice President)
Session detail
Allows attendees to send short textual feedback to the organizer for a session. This is only sent to the organizer and not the speakers.
To respect data privacy rules, this option only displays profiles of attendees who have chosen to share their profile information publicly.